Multi-Disease Deep Brain Stimulation

O10: Deep Brain Stimulation and Psychiatry

The use of deep brain stimulation in psychiatric disorders has received great interest owing to the small risk of the operation, the reversible nature of the technique, and the possibility of optimizing treatment postoperatively. Currently deep brain stimulation in psychiatry is investigated for obsessive-compulsive disorder, Gilles de la Tourette’s syndrome and major depression. This presentat...

deep brain stimulation and gene expression alterations in parkinson’s disease

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Deep Brain Stimulation and Gene Expression Alterations in Parkinson’s Disease

Deep-Brain Stimulation for Parkinson’s Disease

n engl j med 367;16 nejm.org october 18, 2012 1529 This Journal feature begins with a case vignette that includes a therapeutic recommendation. A discussion of the clinical problem and the mechanism of benefit of this form of therapy follows. Major clinical studies, the clinical use of this therapy, and potential adverse effects are reviewed. Relevant formal guidelines, if they exist, are prese...

Thalamic Deep Brain Stimulation for Parkinson’s Disease

With recent advances in neuroimaging and neurosurgical techniques as well as better understanding of functional motor brain circuits, there is increasing evidence that electrical deep brain stimulation (DBS) can be a powerful and safe therapeutic option for medically intractable movement disorders and neuropsychiatric diseases. For more than half a century, the ventrolateral (VL) nucleus of the...